The effects of Cordyceps Sinensis on Glucose Metabolism
Numerous animal studies have shown that Cordyceps sinensis helps in preventing hyperglycemia (diabetes type 1 or 2) and provides improvements in the (peripheral) insulin sensitivity.
Cordyceps provides for: improvement of insulin secretion by the pancreas and / or inhibition of insulin degradation, reduction of oxidative stress, improvement of glucose-regulating enzymes in the liver (glucokinase, hexokinase), promoting a gradual absorption of glucose from the gastrointestinal tract. In an animal model for insulin-dependent diabetes were orally administered preparations of the mycelium and fruiting bodies of Cordyceps sinensis have similar anti-hyperglycemic effect (determined by oral glucose tolerance test, postprandial * and fasting blood glucose and serum fructosamine). with diabetes, the animals ate and drank less and had less weight than the controls, suggesting that Cordyceps diabetes and liver dysfunction associated catabolism * counters.
More research is desirable to determine whether supplementation with Cordyceps sinensis in diabetics and people with an increased risk of diabetes by insulin resistance (metabolic syndrome) helps to improve glucose metabolism.
In a clinical study, 95% of the diabetic C 3 grams sinensis daily intakes, glycemic levels seen, compared to 54% in the group receiving another treatment was given. In healthy subjects took Cordyceps (3 grams per day) also improved glycemic control with less pronounced fluctuations of glucose over during the day (within the normal range).
The effects of Cordyceps Sinensis on Mood and cognition
The risk of cognitive decline and dementia increases with age. Researchers have found a significant increase in the activity of antioxidant enzymes (glutathione peroxidase, superoxidedismutase, catalase), whose activity was decreased by the aging process. The (ultra) structure of the hippocampus, a brain area in which degenerative changes had occurred, increased strongly by supplementation with Cordyceps. The research suggests that Cordyceps sinensis helps keep the brains healthy with age, both structurally and functionally, partly by improving the antioxidant status.
Since fatigue and depression are closely linked, researchers wanted to know if Cordyceps sinensis has an antidepressant effect. They found confirmation of this hypothesis in a widely used animal model for depression (tail suspension test), in which cordyceps extract (obtained by supercritical fluid extraction with CO2) a significant antidepressant effect showed. The researchers found that the antidepressant activity partly based on influencing the adrenergic * and dopaminergic * systems (and not the serotonergic system). According to the “monoamine hypothesis” monoamines * (norepinephrine, dopamine, serotonin) play an important role in the development of depression symptoms.
Other species of Cordyceps
This website is dedicated to the almost magically healthy mushroom Cordyceps sinensis. But there are other types of Cordyceps, and this fascinating video shows how – as good news as Cordyceps are for humans – quite the opposite is true for insects. The “killer fungus” infects insects, kills them, and turns them into a source of food!
Cordyceps sinensis and Celiac disease
There is no cure for Celiac disease, other than completely eliminating gluten from the diet. People with celiac disease who do not get a Celiac disease diagnosis for a long time, can suffer from serious conditions as a result. Cordyceps sinensis has been shown to have a positive effect on people recovering from celiac disease. People who are not sure if they are able to tolerate gluten should consider getting a gluten intolerance test. Once gluten intolerance has been determined, further testing is needed to determine Celiac disease.